Public health nurses (PHNs) are expected to contribute more to implementing the Universal Health Care Act (2019) by performing their roles as leaders, managers, and collaborators in different public health settings. There is a need for public health nurses to take the lead role in planning, designing, implementing, and evaluating health programs and services for universal health coverage. This study aims to describe the development of an online course on leadership, management, and collaborative roles of public health nurses to help improve the quality of care and contribute to strengthening the public health system. An advanced public health nursing course was developed and evaluated using the Analysis Design, Development, Implementation, and Evaluation (ADDIE) model. The course goal is to help prepare nurses in advanced practice in public health nursing to help improve the quality of care through a competent frontline health workforce, contributing to strengthening primary and community-based health systems. The course development was done using a descriptive qualitative design involving the stakeholders' perspectives using the results of a training needs assessment survey and key informant interviews with public health nurse educators. This design entailed purposive sampling to identify participants and public health nursing experts who could contribute to the course activities and translate their insights into their practice settings. Results from the survey on the training needs assessment of target course participants and the key informant interviews with public health nursing experts helped shape the course outcomes, teaching-learning strategies, and evaluation methods. The online program was conducted for six (6) weeks and delivered through synchronous and asynchronous activities using a learning management system and an online meeting platform. Results of the course evaluation after the first implementation showed that many of the participants gave an outstanding rating on the following attainment of course objectives (4.58), completeness of the information provided (4.61), usefulness and relevance of the activity to the needs of the community/beneficiaries (4.69), and contribution of the activity to community development (4.71). Training content was deemed very relevant, timely, and empowering, and helped public health nurses work more systematically and with greater impact on their communities. Participants gave positive reviews with a few recommendations for improving participation.The NurseLEAD course demonstrated how public health nurses deliver primary health care services and manage population-based programs efficiently and effectively, thereby improving the quality of care.