Molecular testing and precision oncology : An overview /
Melisa Styan Burkett
- Vol 54 (12) Pages 46-50 : illustrations ; 27 cm
Abstract: Targeted therapy has emerged as a promising option in cancer treatment, driven by advances in the understanding of DNA changes and the molecular basis of cancer. This article provides an overview of next-generation sequencing and types of genetic alterations, common cancer biomarkers, a review of circulating tumor DNA testing and its applications for oncology treatments, how to read a genomic testing report, examples of targeted therapy for cancer pathologic variants and tumor markers, and the implications for nursing practice in this emerging field.
0360-4039
next-generation sequencing cancer biomarker circulating tumor DNA genomic testing target therapy ctDNA molecular profile molecular testing