TY - BOOK AU - Burkett, Melisa Styan TI - Molecular testing and precision oncology : : An overview SN - 0360-4039 KW - next-generation sequencing KW - cancer biomarker KW - circulating tumor DNA KW - genomic testing KW - target therapy KW - ctDNA KW - molecular profile KW - molecular testing N1 - Abstract: Targeted therapy has emerged as a promising option in cancer treatment, driven by advances in the understanding of DNA changes and the molecular basis of cancer. This article provides an overview of next-generation sequencing and types of genetic alterations, common cancer biomarkers, a review of circulating tumor DNA testing and its applications for oncology treatments, how to read a genomic testing report, examples of targeted therapy for cancer pathologic variants and tumor markers, and the implications for nursing practice in this emerging field ER -