000 01429nam a22001937a 4500
005 20250422093431.0
008 250422b ph ||||| |||| 00| 0 eng d
022 _a0279-3695
040 _cOCT
100 _a Kverno , Karan
240 _aJournal of Psychosocial Nursing and mental health services /
_hNovember 2024
245 _aZuranolone :
_bA rapidly acting oral neuroactive steroid antidepressant for the treatment of postpartum depression /
_cKaran Kverno and Fatima Ramos-Marcuse
300 _aVol 62 (11) Pages 7- 10 :
_billustrations ;
_c27 cm
500 _aABSTRACT Severe depression, anxiety, and mood dysregulation during pregnancy and postpartum are risk factors for the safety and health of mother and baby. Current best practice guidelines recommend screening for depressive and anxiety symptoms before and during pregnancy, in addition to the postpartum period. Rapid identification and treatment of depression has the potential to be life-saving and prevent deleterious consequences, including impaired mother-infant bonding, emotional dysregulation, and other developmental problems. The current article reviews the neurobiological mechanisms of postpartum depression and a novel rapidly acting oral pharmacotherapeutic neuroactive ste-roid, zuranolone.
650 _aoral neuroactive steroid antidepressant
650 _apostpartum depression
700 _a Ramos-Marcuse, Fatima
942 _2ddc
_cCR
_n0
999 _c10345
_d10345