000 00987nam a22001457a 4500
005 20230317112805.0
008 230317b ph ||||| |||| 00| 0 eng d
040 _cOCT
240 _aJournal of psychosocial nursing and mental health services /
_hNovember 2022
245 _aDectromethorphan :
_bfrom cough suppressant to antidepressant
260 _aThorofarem Jersey :
_bSlack Incorporated,
_c2022
300 _aVol. 60 (11) : pages 9-11
500 _aDextromethorphan (DXM) has been repurposed several times over the past 7 decades: first as a cough suppressant, then as a compounded formulation with quinidine for treatment of pseudobulbar affect, and most recently as a compounded formulation with bupropion for treatment of major depressive disorder. The current article describes the history and purported mechanisms of action of DXM for each use and the uniquely rapid action and safety profile of the oral dextromethorphanbupropion antidepressant formulation.
942 _2ddc
_cCR
_n0
999 _c8579
_d8579